别名:Granulins, Proepithelin, PEPI, Acrogranin, Glycoprotein of 88 Kda, Progranulin, Paragranulin, Granulin-1, Granulin G, Granulin-2, Granulin F, Granulin-3, Granulin B, Granulin-4, Granulin A, Granulin-5, Granulin C, Granulin-6, Granulin D, Granulin-7, Granulin E, GRN应用:WB,IHC
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. |
| Specification | |
|---|---|
| Aliases | Granulins, Proepithelin, PEPI, Acrogranin, Glycoprotein of 88 Kda, Progranulin, Paragranulin, Granulin-1, Granulin G, Granulin-2, Granulin F, Granulin-3, Granulin B, Granulin-4, Granulin A, Granulin-5, Granulin C, Granulin-6, Granulin D, Granulin-7, Granulin E, GRN |
| Entrez GeneID | 2896 |
| Swissprot | P28799 |
| WB Predicted band size | 63.5kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
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GRN Antibody (C-term) (Cat. #P32493) western blot analysis in A2058,HepG2,HL-60,T47D cell line lysates (35ug/lane).This demonstrates the GRN antibody detected the GRN protein (arrow). |
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Immunohistochemical analysis of paraffin-embedded H. kidney section using GRN Antibody (C-term)(Cat#P32493). P32493 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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