Rabbit Polyclonal Antibody to GRTP1

包装: 1G|100G|500G|1KG|100KG

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别名:TBC1D6
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
GRTP1 (Growth hormone-regulated TBC protein 1), also designated TBC1 domain family member 6, is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. May act as a GTPase-activating protein for Rab family protein(s).

Description

GRTP1 (Growth hormone-regulated TBC protein 1), also designated TBC1 domain family member 6, is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. May act as a GTPase-activating protein for Rab family protein(s).

Specification
Aliases	TBC1D6
Swissprot	Q5TC63
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human GRTP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/25-1/50
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer using P06659(GRTP1 Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human colorectal cancer using P06659(GRTP1 Antibody) at dilution 1/40. (Original magnification: ×200)