Rabbit Polyclonal Antibody to GSTP1

包装: 1G|100G|500G|1KG|100KG

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别名:Glutathione S-transferase P, GST class-pi, GSTP1-1, GSTP1, FAEES3, GST3
应用:WB,ICC,FCM
反应种属:Human, Rat
规格：50μl/100μl

Description
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Description

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Specification
Aliases	Glutathione S-transferase P, GST class-pi, GSTP1-1, GSTP1, FAEES3, GST3
Entrez GeneID	2950
Swissprot	P09211
WB Predicted band size	23.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat
Immunogen	This GSTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-192 amino acids from the C-terminal region of human GSTP1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application
WB	1/1000
ICC	1/10-1/50
FCM	1/10-1/50

	GSTP1 Antibody (C-term) (Cat. #P30407) western blot analysis in K562,PC-3,Y79 cell line lysates (35ug/lane).This demonstrates the GSTP1 antibody detected the GSTP1 protein (arrow).
	Confocal immunofluorescent analysis of GSTP1 Antibody (C-term)(Cat#P30407) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
	Flow cytometric analysis of widr cells using GSTP1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.