Rabbit Polyclonal Antibody to GTF2A1L

包装: 1G|100G|500G|1KG|100KG

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别名:TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
应用:WB
反应种属:Human
规格：50μl/100μl

Description
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Description

The assembly and stability of the RNA polymerase II
transcription pre-initiation complex on a eukaryotic core promoter
involve the effects of TFIIA on the interaction between
TATA-binding protein (TBP) and DNA. This gene encodes a germ
cell-specific counterpart of the large (alpha/beta) subunit of
general transcription factor TFIIA that is able to stabilize the
binding of TBP to DNA and may be uniquely important to testis
biology. Alternative splicing for this locus has been observed and
two variants, encoding distinct isoforms, have been identified.
Co-transcription of this gene and the neighboring upstream gene
generates a rare transcript (SALF), which encodes a fusion protein
comprised of sequence sharing identity with each individual gene
product.

Specification
Aliases	TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
Entrez GeneID	11036
Swissprot	Q9UNN4
WB Predicted band size	52.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This GTF2A1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human GTF2A1L.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.