Rabbit Polyclonal Antibody to GTF2IRD1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:CREAM1; G2D1; GT2D1; GTF2I repeat domain containing protein 1; GTF2IRD1
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 By similarity.Yan X., Biochem. J. 345:749-757(2000).Hillier L.W., Nature 424:157-164(2003).Tussie-Luna M.I., Proc. Natl. Acad. Sci. U.S.A. 98:7789-7794(2001).

Description

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 By similarity.Yan X., Biochem. J. 345:749-757(2000).Hillier L.W., Nature 424:157-164(2003).Tussie-Luna M.I., Proc. Natl. Acad. Sci. U.S.A. 98:7789-7794(2001).

Specification
Aliases	CREAM1; G2D1; GT2D1; GTF2I repeat domain containing protein 1; GTF2IRD1
Entrez GeneID	9569;
Swissprot	Q9UHL9
WB Predicted band size	106kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from N-terminal of human GTF2IRD1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.