中文 
别名:Histone H33, H3f3a, H33a应用:WB
反应种属:Mouse
规格：50μl/100μl
| Description |
|---|
| Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Specification | |
|---|---|
| Aliases | Histone H33, H3f3a, H33a |
| Entrez GeneID | 15078;15081 |
| Swissprot | P84244 |
| WB Predicted band size | 15.3kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-136 amino acids from mouse H3f3b. |
| Application | |
|---|---|
| WB | 1/2000-1/8000 |
 |
All lanes : Anti-H3f3b Antibody (C-Term) at 1:2000 dilution Lane 1: mouse cerebellum lysate Lane 2: mouse spleen lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 15 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
 |
All lanes : Anti-H3f3b Antibody (C-Term) at 1:8000 dilution Lane 1: NIH/3T3 whole cell lysate Lane 2: mouse lung lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 15 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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