Rabbit Polyclonal Antibody to HBA2

包装: 1G|100G|500G|1KG|100KG

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别名:Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
应用:WB
反应种属:Human, Mouse
规格：50μl/100μl

Description
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5′- zeta – pseudozeta – mu – pseudoalpha-1 – alpha-2 – alpha-1 – theta – 3′. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5′ untranslated regions and the introns, but they differ significantly over the 3′ untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Description

HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5′- zeta – pseudozeta – mu – pseudoalpha-1 – alpha-2 – alpha-1 – theta – 3′. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5′ untranslated regions and the introns, but they differ significantly over the 3′ untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Specification
Aliases	Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
Entrez GeneID	3039;3040
Swissprot	P69905
WB Predicted band size	15.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.