Rabbit Polyclonal Antibody to HBQ1 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin, HBQ1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5′ – zeta – pseudozeta – mu – pseudoalpha-2 -pseudoalpha-1 – alpha-2 – alpha-1 – theta-1 – 3′. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.

Description

Theta-globin mRNA is found in human fetal erythroid tissue
but not in adult erythroid or other nonerythroid tissue. The
theta-1 gene may be expressed very early in embryonic life, perhaps
sometime before 5 weeks. Theta-1 is a member of the human
alpha-globin gene cluster that involves five functional genes and
two pseudogenes. The order of genes is: 5′ – zeta – pseudozeta – mu
– pseudoalpha-2 -pseudoalpha-1 – alpha-2 – alpha-1 – theta-1 – 3′.
Research supports a transcriptionally active role for the gene and
a functional role for the peptide in specific cells, possibly those
of early erythroid tissue.

Specification
Aliases	Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin, HBQ1
Entrez GeneID	3049
Swissprot	P09105
WB Predicted band size	15.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This HBQ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human HBQ1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	HBQ1 Antibody (N-term) (Cat. #P31195) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HBQ1 antibody detected the HBQ1 protein (arrow).
	HBQ1 Antibody (N-term) (Cat. #P31195)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HBQ1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.