Rabbit Polyclonal Antibody to HDAC3

包装: 1G|100G|500G|1KG|100KG

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别名:HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1.

Description

HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1.

Specification
Aliases	HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
Entrez GeneID	8841
Swissprot	O15379
WB Predicted band size	Calculated MW: 49 kDa; Observed MW: 49 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.420~424(N-D-K-E-S) derived from Human HDAC3.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.