中文 
别名:HD6; HDA6; Histone deacetylase 6; JM21;应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes By similarity. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.Chen S, Owens GC, Makarenkova H, Edelman DB (2010)PLoS One 5, e10848. |
| Specification | |
|---|---|
| Aliases | HD6; HDA6; Histone deacetylase 6; JM21; |
| Entrez GeneID | 10013; |
| Swissprot | Q9UBN7 |
| WB Predicted band size | 131kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of serine 22 (P-Q-S(p)-P-P) derived from Human HDAC6. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) antibody P40618.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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