别名:HD7a; HDA7; HDAC7A;应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Walsh M.J., Submitted (FEB-2000)Zelent A., Submitted (MAY-2003)Sugano S., Nat. Genet. 36:40-45(2004) |
Specification | |
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Aliases | HD7a; HDA7; HDAC7A; |
Entrez GeneID | 51564; |
Swissprot | Q8WUI4 |
WB Predicted band size | 103kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Peptide sequence around phosphorylation site of Serine 155(T-V-S(p)-E-P) derived from Human HDAC7A. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody P40522.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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