Rabbit Polyclonal Antibody to HIST3H3

包装: 1G|100G|500G|1KG|100KG

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别名:Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq].

Description

Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
wrapped around a histone octamer composed of pairs of each of the
four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
further compacted through the interaction of a linker histone, H1,
with the DNA between the nucleosomes to form higher order chromatin
structures. This gene is intronless and encodes a member of the
histone H3 family. Transcripts from this gene lack polyA tails;
instead, they contain a palindromic termination element. This gene
is located separately from the other H3 genes that are in the
histone gene cluster on chromosome 6p22-p21.3. [provided by
RefSeq].

Specification
Aliases	Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
Entrez GeneID	8290
Swissprot	Q16695
WB Predicted band size	15.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This HIST3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the Central region of human HIST3H3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	HIST3H3 Antibody (Center) (Cat. #P31055) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the HIST3H3 antibody detected the HIST3H3 protein (arrow).
	HIST3H3 Antibody (Center) (Cat. #P31055) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.