Rabbit Polyclonal Antibody to Histone H2A

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别名:HIST1H2AB; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; H2AFM
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specification
Aliases	HIST1H2AB; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; H2AFM
Entrez GeneID	3012
Swissprot	P04908
WB Predicted band size	Calculated MW: 14 kDa; Observed MW: 14 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Histone H2A.Z
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Histone H2A.Z in(1)Neuro2a lysates;(2)HeLa lysates using Histone H2A antibody.
	Immunohistochemistry analysis of paraffin-embedded Human kidney using Histone H2A.Z antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.