Rabbit Polyclonal Antibody to Histone H3 (Di-Methyl-Lys27)

包装: 1G|100G|500G|1KG|100KG

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别名:H3/a, H3/c, H3/d, H3/f, H3/h
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specification
Aliases	H3/a, H3/c, H3/d, H3/f, H3/h
Entrez GeneID	8350;8351;8352;8353;8354;8355;8356;8357;8358;8968;
Swissprot	P68431
WB Predicted band size	17kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around Di-Methylation site of lysine 27(A-R-K(di-methyl)-S-A) derived from Human Histone H3.
Formulation	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of extracts from C6 and Hela cells using Histone H3 (Di-Methyl-Lys27) Antibody P40347.
	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Histone H3 (Di-Methyl-Lys27) Antibody P40347.