Rabbit Polyclonal Antibody to HLA DQB1/2

包装: 1G|100G|500G|1KG|100KG

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别名:HLA-DQB1; HLA-DQB; HLA class II histocompatibility antigen; DQ beta 1 chain; MHC class II antigen DQB1; HLA-DQB2; HLA-DXB; HLA class II histocompatibility antigen; DQ beta 2 chainHLA class II histocompatibility antigen; DX beta chain; MHC class II antigen DQB2
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.

Description

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.

Specification
Aliases	HLA-DQB1; HLA-DQB; HLA class II histocompatibility antigen; DQ beta 1 chain; MHC class II antigen DQB1; HLA-DQB2; HLA-DXB; HLA class II histocompatibility antigen; DQ beta 2 chainHLA class II histocompatibility antigen; DX beta chain; MHC class II antigen DQB2
Entrez GeneID	3119/3120
Swissprot	P01920/P05538
WB Predicted band size	Calculated MW: 30 kDa; Observed MW: 30 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human HLA-DQB1/HLA-DQB2. AA range:131-180
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ELISA	1/10000

	Western blot analysis of HLA DQB1/2 in PC-12 lysates using HLA DQB1/2 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human colon using HLA DQB1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded Human colon using HLA DQB1/2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded Human spleen using HLA DQB1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.