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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to HLA-DQB2

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别名:DQB2; HLA-DXB; HLA-DQB1
应用:IHC
反应种属:Human
规格:50μl/100μl

Description
HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.
Specification
Aliases DQB2; HLA-DXB; HLA-DQB1
Swissprot P05538
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human HLA-DQB2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/50-1/200
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P03319(HLA-DQB2 Antibody) at dilution 1/70. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。