Rabbit Polyclonal Antibody to HNRNPC

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].

Description

This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene can act
as a tetramer and is involved in the assembly of 40S hnRNP
particles. Multiple transcript variants encoding at least two
different isoforms have been described for this gene. [provided by
RefSeq].

Specification
Aliases	Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
Entrez GeneID	3183
Swissprot	P07910
WB Predicted band size	33.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	HNRNPC Antibody (C-term) (Cat. #P30837) western blot analysis in Jurkat,K562,U251 cell line lysates (35ug/lane).This demonstrates the HNRNPC antibody detected the HNRNPC protein (arrow).
	HNRNPC antibody (C-term) (Cat. #P30837) immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HNRNPC antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.