Rabbit Polyclonal Antibody to HNRNPR (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Heterogeneous nuclear ribonucleoprotein R, hnRNP R, HNRNPR, HNRPR
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Description

This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that bind to RNAs and also contains a
nuclear localization motif. Multiple alternatively spliced
transcript variants have been found for this gene. [provided by
RefSeq].

Specification
Aliases	Heterogeneous nuclear ribonucleoprotein R, hnRNP R, HNRNPR, HNRPR
Entrez GeneID	10236
Swissprot	O43390
WB Predicted band size	70.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This HNRNPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human HNRNPR.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000

	HNRNPR Antibody (N-term) (Cat. #P31761) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNRNPR antibody detected the HNRNPR protein (arrow).
	Western blot analysis of HNRNPR (arrow) using rabbit polyclonal HNRNPR Antibody (N-term) (Cat. #P31761). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HNRNPR gene.