Rabbit Polyclonal Antibody to HOPX

包装: 1G|100G|500G|1KG|100KG

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别名:Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX, HOD, HOP, LAGY, NECC1, OB1
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq].

Description

The protein encoded by this gene is a homeodomain protein
that lacks certain conserved residues required for DNA binding. It
was reported that choriocarcinoma cell lines and tissues failed to
express this gene, which suggested the possible involvement of this
gene in malignant conversion of placental trophoblasts. Studies in
mice suggest that this protein may interact with serum response
factor (SRF) and modulate SRF-dependent cardiac-specific gene
expression and cardiac development. Multiple alternatively spliced
transcript variants have been identified for this gene. [provided
by RefSeq].

Specification
Aliases	Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX, HOD, HOP, LAGY, NECC1, OB1
Entrez GeneID	84525
Swissprot	Q9BPY8
WB Predicted band size	8.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This HOPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the C-terminal region of human HOPX.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	HOPX Antibody (C-term) (Cat. #P30962) western blot analysis in Ramos,A2058,293 cell line lysates (35ug/lane).This demonstrates the HOPX antibody detected the HOPX protein (arrow).
	HOPX Antibody (C-term) (Cat. #P30962) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.