Rabbit Polyclonal Antibody to HOXA11

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别名:homeobox A11, HOX1, HOX1I
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Description

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Specification
Aliases	homeobox A11, HOX1, HOX1I
Entrez GeneID	3207;
Swissprot	P31270
WB Predicted band size	34kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide corresponding to a region derived from 144-159 amino acids of Human homeobox A11
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	110-1/50
ELISA	1:1000-1:2000

	Gel: 10%SDS-PAGE Lysate: 40ug Hela cell lysate Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG – H&L (HRP) at 1/10000 dilution Exposure time: 5 minutes
	The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 31221 (HOXA11 Antibody) at dilution 1/10, on the right is treated with the synthetic peptide.