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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to HP1γ (Phospho-Ser93)

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别名:HECH; HP1 gamma; HP1Hs-gamma; chromobox 3;
应用:WB
反应种属:Human
规格:50μl/100μl

Description
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5′ UTR, have been found for this gene.Ye Q., J. Biol. Chem. 271:14653-14656(1996)Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databasesKoike N., FEBS Lett. 467:17-21(2000)
Specification
Aliases HECH; HP1 gamma; HP1Hs-gamma; chromobox 3;
Entrez GeneID 11335;
Swissprot Q13185
WB Predicted band size 24kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of Serine 93(R-L-S(p)-L-S) derived from Human HP1γ .
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/1000

Western blot analysis of extracts from K562 cells treated with forskolin using HP1γ(Phospho-Ser93) Antibody P40469.The lane on the right is treated with the antigen-specific peptide.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。