Rabbit Polyclonal Antibody to HSD3B7

包装: 1G|100G|500G|1KG|100KG

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别名:CBAS1; PFIC4; SDR11E3
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	CBAS1; PFIC4; SDR11E3
Swissprot	Q9H2F3
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human HSD3B7
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P01458(HSD3B7 Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P01458(HSD3B7 Antibody) at dilution 1/40. (Original magnification: ×200)