Rabbit Polyclonal Antibody to HTATIP2 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Oxidoreductase HTATIP2, 111-, 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2, HTATIP2 (HGNC:16637)
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

Description

Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

Specification
Aliases	Oxidoreductase HTATIP2, 111-, 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2, HTATIP2 (HGNC:16637)
Entrez GeneID	10553
Swissprot	Q9BUP3
WB Predicted band size	27.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This HTATIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human HTATIP2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	HTATIP2 Antibody (N-term) (Cat. #P31527) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HTATIP2 antibody detected the HTATIP2 protein (arrow).
	HTATIP2 Antibody (N-term) (P31527)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HTATIP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.