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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to HUMAN-RIN1(Y36)

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别名:Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Specification
Aliases Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
Entrez GeneID 9610
Swissprot Q13671
WB Predicted band size 84.1kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Western blot analysis of lysate from U-87 MG cell line, using Phospho-HUMAN-RIN1(Y36). ctrl(Cat. #P32772). P32772 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。