Rabbit Polyclonal Antibody to IDO 2

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:IDO2; INDOL1; Indoleamine 2; 3-dioxygenase 2; IDO-2; Indoleamine 2; 3-dioxygenase-like protein 1; Indoleamine-pyrrole 2; 3-dioxygenase-like protein 1
应用:WB
反应种属:Human
规格：50μl/100μl

Description
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Description

INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Specification
Aliases	IDO2; INDOL1; Indoleamine 2; 3-dioxygenase 2; IDO-2; Indoleamine 2; 3-dioxygenase-like protein 1; Indoleamine-pyrrole 2; 3-dioxygenase-like protein 1
Entrez GeneID	169355
Swissprot	Q6ZQW0
WB Predicted band size	Calculated MW: 47 kDa; Observed MW: 47 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human IDO2. AA range:101-150
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.