Rabbit Polyclonal Antibody to IFRD2

包装: 1G|100G|500G|1KG|100KG

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别名:SM15; IFNRP; SKMc15
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.

Description

IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.

Specification
Aliases	SM15; IFNRP; SKMc15
Swissprot	Q12894
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human IFRD2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/30-1/150
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P02721(IFRD2 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P02721(IFRD2 Antibody) at dilution 1/20. (Original magnification: ×200)