Rabbit Polyclonal Antibody to IGF2BP3

包装: 1G|100G|500G|1KG|100KG

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别名:KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Description

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Specification
Aliases	KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
Swissprot	O00425
WB Predicted band size	64 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human IGF2BP3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/25-1/100
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: HEPG2, K562, 293T and Hela cell lysates, Primary antibody: P12758(IGF2BP3 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P12758(IGF2BP3 Antibody) at dilution 1/30. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12758(IGF2BP3 Antibody) at dilution 1/30. (Original magnification: ×200)