Rabbit Polyclonal Antibody to IGSF8

包装: 1G|100G|500G|1KG|100KG

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别名:EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Description

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Specification
Aliases	EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1
Entrez GeneID	93185;
Swissprot	Q969P0
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to a region derived from internal residues of human immunoglobulin superfamily, member 8
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
IHC	1/25-1/100

	Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42771 at dilution 1/15.
	Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42771 at dilution 1/15.