中文 
别名:FIP3; IKBKG; IKKAP1; IKKG; NF-kappaB应用:IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999)Jin D.-Y., J. Biomed. Sci. 6:115-120(1999)Rothwarf D.M., Nature 395:297-300(1998). |
| Specification | |
|---|---|
| Aliases | FIP3; IKBKG; IKKAP1; IKKG; NF-kappaB |
| Entrez GeneID | 8517; |
| Swissprot | Q9Y6K9 |
| WB Predicted band size | 48kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 376(Y-L-S(p)-S-P) derived from Human IKK-γ. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
 |
Immunohistochemical analysis of paraffin-embedded human brain tissue using IKK-γ (Phospho-Ser376) antibody P40436 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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