中文 
别名:CD212; IL12RB; IL-12R-BETA1应用:IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Specification | |
|---|---|
| Aliases | CD212; IL12RB; IL-12R-BETA1 |
| Entrez GeneID | 3594; |
| Swissprot | P42701 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human interleukin 12 receptor, beta 1 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| IHC | 1/25-1/100 |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42753 at dilution 1/15. |
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Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42753 at dilution 1/15. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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