中文 
别名:ILK1; p59ILK; kinase ILK;应用:IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.Hannigan G.E., Nature 379:91-96(1996)Janji B., Oncogene 19:3069-3077(2000)Tadic B., Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. |
| Specification | |
|---|---|
| Aliases | ILK1; p59ILK; kinase ILK; |
| Entrez GeneID | 3611; |
| Swissprot | Q13418 |
| WB Predicted band size | 51kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human brain tissue using ILK (Phospho-Ser246) antibody P40437 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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