库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to INHBA

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别名:EDF, FRP
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Specification
Aliases EDF, FRP
Swissprot P08476
WB Predicted band size 47 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human INHBA
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/1000-1/2000
ELISA 1/2000-1/10000

Gel: 8+10%SDS-PAGE, Lysate: 30 μg, Lane: Mouse fat tissue, Primary antibody: P10704(INHBA Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。