别名:HEP-NOS; NOS2; inducible;应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993)Sherman P.A., Biochemistry 32:11600-11605(1993)Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993) |
Specification | |
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Aliases | HEP-NOS; NOS2; inducible; |
Entrez GeneID | 4843; |
Swissprot | P35228 |
WB Predicted band size | 131kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 151(Q-Y-Y(p)-G-S) derived from Human iNOS . |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Inos (Phospho-Tyr151) antibody P40467 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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