Rabbit Polyclonal Antibody to INPP5B

包装: 1G|100G|500G|1KG|100KG

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别名:Type II inositol 1,5-trisphosphate 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, 5PTase, INPP5B, OCRL2
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].

Description

Cellular calcium signaling is controlled by the production
of inositol phosphates (IPs) by phospholipase C in response to
extracellular signals. The IP signaling molecules are inactivated
by a family of inositol polyphosphate-5-phosphatases
(5-phosphatases). INPP5B encodes the type II 5-phosphatase. The
protein is localized to the cytosol and mitochondria, and
associates with membranes through an isoprenyl modification near
the C-terminus. Several alternatively spliced transcript variants
of this gene have been described, but the full-length nature of
some of these variants has not been determined. [provided by
RefSeq].

Specification
Aliases	Type II inositol 1,5-trisphosphate 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, 5PTase, INPP5B, OCRL2
Entrez GeneID	3633
Swissprot	P32019
WB Predicted band size	112.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.