别名:IL1RAK; IRAK; mPLK;应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.Cao Z., Science 271:1128-1131(1996)Reichwald K., Mamm. Genome 11:182-190(2000)Jensen L.E., J. Biol. Chem. 276:29037-29044(2001). |
Specification | |
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Aliases | IL1RAK; IRAK; mPLK; |
Entrez GeneID | 3654; |
Swissprot | P51617 |
WB Predicted band size | 76kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody P40439 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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