Rabbit Polyclonal Antibody to ISWI

包装: 1G|100G|500G|1KG|100KG

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别名:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, 364-, Sucrose nonfermenting protein 2 homolog, hSNF2H, SMARCA5, SNF2H, WCRF135
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.

Description

The protein encoded by this gene is a member of the
SWI/SNF family of proteins. Members of this family have helicase
and ATPase activities and are thought to regulate transcription of
certain genes by altering the chromatin structure around those
genes. The protein encoded by this gene is a component of the
chromatin remodeling and spacing factor RSF, a facilitator of the
transcription of class II genes by RNA polymerase II. The encoded
protein is similar in sequence to the Drosophila ISWI chromatin
remodeling protein.

Specification
Aliases	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, 364-, Sucrose nonfermenting protein 2 homolog, hSNF2H, SMARCA5, SNF2H, WCRF135
Entrez GeneID	8467
Swissprot	O60264
WB Predicted band size	121.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This ISWI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human ISWI.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	ISWI Antibody (C-term) (Cat. #P30975) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ISWI antibody detected the ISWI protein (arrow).
	ISWI Antibody (C-term) (Cat. #P30975) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.