Rabbit Polyclonal Antibody to ITGA11 (N-term)

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别名:Integrin alpha-11, ITGA11
应用:WB,FCM
反应种属:Human, Hamster, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.

Description

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.

Specification
Aliases	Integrin alpha-11, ITGA11
Entrez GeneID	22801
Swissprot	Q9UKX5
WB Predicted band size	133.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Hamster, Mouse, Rat
Immunogen	This ITGA11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the N-terminal region of human ITGA11.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	All lanes : Anti-ITGA11 Antibody (N-term) at 1:1000 dilution Lane 1: Neuro-2a whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution. Observed band size : 133kDa Blocking/Dilution buffer: 5% NFDM/TBST.
	ITGA11 Antibody (N-term) (Cat. #P35041) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the ITGA11 antibody detected the ITGA11 protein (arrow).
	ITGA11 Antibody (N-term) (Cat. #P35041) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the ITGA11 antibody detected the ITGA11 protein (arrow).
	ITGA11 Antibody (N-term) (Cat. #P35041) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.