别名:Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8应用:WB
反应种属:Human, Mouse
规格:50μl/100μl
Description |
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Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. |
Specification | |
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Aliases | Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8 |
Entrez GeneID | 8516 |
Swissprot | P53708 |
WB Predicted band size | 117.5kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Application | |
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WB | 1/2000 |
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Anti-ITGA8 Antibody (C-term) at 1:2000 dilution + K562 whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 117 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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All lanes : Anti-ITGA8 Antibody (C-term) at 1:2000 dilution Lane 1: Raji whole cell lysate Lane 2: 293 whole cell lysate Lane 3: LNCaP whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 117 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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