Rabbit Polyclonal Antibody to ITGAL

包装: 1G|100G|500G|1KG|100KG

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别名:CD11A, LFA-1, LFA1A
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Description

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	CD11A, LFA-1, LFA1A
Swissprot	P20701
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human ITGAL
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/15-1/50
ELISA	1/1000-1/2000

	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P04084(ITGAL Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P04084(ITGAL Antibody) at dilution 1/20. (Original magnification: ×200)