别名:integrin beta 3 binding protein (beta3-endonexin), CENPR, NRIF3, TAP20, CENP-R, HSU37139应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
| Specification | |
|---|---|
| Aliases | integrin beta 3 binding protein (beta3-endonexin), CENPR, NRIF3, TAP20, CENP-R, HSU37139 |
| Entrez GeneID | 23421; |
| Swissprot | Q13352 |
| WB Predicted band size | 15kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Full length fusion protein |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| ELISA | 1:1000-1:5000 |
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Gel: 15%+12%+10%SDS-PAGE Lane1: Jurkat cell lysate Lane2: 231 cell lysate Lysates: 50ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG – H&L (HRP) at 1/10000 dilution Exposure time: 3 seconds |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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