别名:CD104 antigen; GP150; ITB4; integrin beta-4; integrin beta-4C应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
---|
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.Suzuki S., EMBO J. 9:757-763(1990).Hogervorst F., EMBO J. 9:765-770(1990).Tamura R.N., J. Cell Biol. 111:1593-1604(1990). |
Specification | |
---|---|
Aliases | CD104 antigen; GP150; ITB4; integrin beta-4; integrin beta-4C |
Entrez GeneID | 3691; |
Swissprot | P16144 |
WB Predicted band size | 202kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T). |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
---|---|
WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
![]() |
Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using ITGB4 (Ab-1510) antibody P41673. |
![]() |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ITGB4 (Ab-1510) antibody P41673. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复