库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to KCNH2

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别名:ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
Specification
Aliases ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
Swissprot Q12809
WB Predicted band size 90 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human KCNH2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/500-1/2000
ELISA 1/1000-1/5000

Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane: Mouse brain tissue, Primary antibody: P04017(KCNH2 Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。