别名:Hippocampal inward rectifier; HIRK2; HRK1; Inward rectifier K channel Kir2.3; Inward rectifier potassium channel 4应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium By similarity.Perier F., Proc. Natl. Acad. Sci. U.S.A. 91:6240-6244(1994).Tang W., FEBS Lett. 348:239-243(1994).Makhina E.N., J. Biol. Chem. 269:20468-20474(1994). |
Specification | |
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Aliases | Hippocampal inward rectifier; HIRK2; HRK1; Inward rectifier K channel Kir2.3; Inward rectifier potassium channel 4 |
Entrez GeneID | 3761; |
Swissprot | P48050 |
WB Predicted band size | 50kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human KCNJ4. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from 293 cells and NIH/3T3 cells, using KCNJ4 antibody P42731. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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