Rabbit Polyclonal Antibody to KCNK3

包装: 1G|100G|500G|1KG|100KG

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别名:TASK; Task-1; cTBAK-1
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.

Description

TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.

Specification
Aliases	TASK; Task-1; cTBAK-1
Entrez GeneID	16527;
Swissprot	O35111
WB Predicted band size	45kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide corresponding to residues near the C terminal of human potassium channel, subfamily K, member 3
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	110-1/50

	Gel: 8%SDS-PAGE Lysate: 40ug Mouse heart tissuePrimary antibody: 1/200 dilution Secondary antibody dilution: 1/8000Exposure time: 10 seconds
	Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42994 at dilution 1/20.