Rabbit Polyclonal Antibody to KCNV2

包装: 1G|100G|500G|1KG|100KG

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别名:Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a ‘silent subunit’, and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

Description

Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. This gene encodes a member of
the potassium voltage-gated channel subfamily V. This member is
identified as a ‘silent subunit’, and it does not form
homomultimers, but forms heteromultimers with several other
subfamily members. Through obligatory heteromerization, it exerts a
function-altering effect on other potassium channel subunits. This
protein is strongly expressed in pancreas and has a weaker
expression in several other tissues.

Specification
Aliases	Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2
Entrez GeneID	169522
Swissprot	Q8TDN2
WB Predicted band size	62.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	KCNV2 Antibody (C-term) (Cat. #P31217) western blot analysis in 293,K562,HepG2,Jurkat,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNV2 antibody detected the KCNV2 protein (arrow).
	KCNV2 Antibody (C-term) (Cat. #P31217)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNV2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.