中文 
别名:Lysine-specific histone demethylase 1B, 1—, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, KDM1B, AOF1, C6orf193, LSD2应用:WB
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| Histone demethylase that demethylates ‘Lys-4’ of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated ‘Lys-4’ of histone H3. Has no effect on tri- methylated ‘Lys-4’, mono-, di- or tri-methylated ‘Lys-9’, mono-, di- or tri-methylated ‘Lys-27’, mono-, di- or tri-methylated ‘Lys- 36’ of histone H3, or on mono-, di- or tri-methylated ‘Lys-20’ of histone H4 (By similarity). |
| Specification | |
|---|---|
| Aliases | Lysine-specific histone demethylase 1B, 1—, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, KDM1B, AOF1, C6orf193, LSD2 |
| Entrez GeneID | 221656 |
| Swissprot | Q8NB78 |
| WB Predicted band size | 92.1kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This KDM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 38-73 amino acids from the N-terminal region of human KDM1B. |
| Application | |
|---|---|
| WB | 1/1000 |
 |
Western blot analysis of lysates from Raji, K562 cell line (from left to right), using KDM1B Antibody (N-term)(Cat. #P32912). P32912 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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