别名:GASC1; JHDM3C; JMJD2C; TDRD14C; bA146B14.1应用:WB
反应种属:Human, Mouse
规格:50μl/100μl
| Description |
|---|
| This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. |
| Specification | |
|---|---|
| Aliases | GASC1; JHDM3C; JMJD2C; TDRD14C; bA146B14.1 |
| Swissprot | Q9H3R0 |
| WB Predicted band size | 120 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human KDM4C |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/2000-1/5000 |
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse heart tissue, Mouse brain tissue, Primary antibody: P04987(KDM4C Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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