Rabbit Polyclonal Antibody to KDM5A

包装: 1G|100G|500G|1KG|100KG

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别名:RBP2; RBBP2; RBBP-2
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

Description

This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

Specification
Aliases	RBP2; RBBP2; RBBP-2
Entrez GeneID	5927;
Swissprot	P29375
WB Predicted band size	192kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 5A
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	1/50-1/300

	Gel: 6%SDS-PAGELysate: 40 ug Lane 1-2: 231 cells, hela cells Primary antibody: KDM5AAntibody at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilutionExposure time: 2 minutes
	The image on the left is immunohistochemistry of paraffin_x005Fembedded Human liver cancer tissue using KDM5A Antibody at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification:x200)
	The image on the left is immunohistochemistry of paraffin_x005Fembedded Human esophagus cancer tissue using KDM5AAntibody at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: 200)