别名:CT31; PLU1; PUT1; PLU-1; JARID1B; RBBP2H1A应用:WB,IHC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin. |
Specification | |
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Aliases | CT31; PLU1; PUT1; PLU-1; JARID1B; RBBP2H1A |
Entrez GeneID | 10765; |
Swissprot | Q9UGL1 |
WB Predicted band size | 176kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 5B |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/200-1/1000 |
IHC | 1/50-1/200 |
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Gel: 6%SDS-PAGE Lysates (from left to right): Hela and MCF-7 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes |
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Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42937 at dilution 1/40. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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