Rabbit Polyclonal Antibody to KIR2DL3/1/4/S4

包装: 1G|100G|500G|1KG|100KG

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别名:p58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB/NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64/ G9P; CD158D; KIR103; KIR103AS/ KKA3; KIR1D; NKAT8; CD158I; KIR412
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several “framework” genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain.

Description

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several “framework” genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain.

Specification
Aliases	p58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB/NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64/ G9P; CD158D; KIR103; KIR103AS/ KKA3; KIR1D; NKAT8; CD158I; KIR412
Entrez GeneID	3804;
Swissprot	P43628
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to a region derived from internal residues of human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3/1/4/ short cytoplasmic tail, 4
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
IHC	1/50-1/100

	Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42816 at dilution 1/30.
	Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42816 at dilution 1/30.